Turkey, which sits on the border of Syria, and is known as a gateway to Europe from Asia and the Middle East, is in a position of serious strategic importance.
Yet, the USA and Ankara have found themselves on different sides of the war in Syria.
Earlier this week, President Donald Trump decided to directly arm Syrian Kurdish militias in the battle against the Islamic State.
But the decision to send weapons and equipment to armed groups known as the People’s Protection Units (YPG) will damage ties with Turkey.
Recep Tayyip Erdogan’s country considers the YPG an extension of the outlawed Kurdistan Workers Party (PKK), which has waged an insurgency in Turkey’s mainly Kurdish southeast for three decades.
Mr Trump’s call could lead to direct confrontation between the US and Turkey since the White House has suggested the YPG is not an extension of the PKK.
In a meeting in London, prime minister for Turkey Binali Yildirim revealed while the issue will undoubtedly be central to talks – there is a more pressing issue on their minds.
The country wants Trump to agree to the extradition of Muhammed Fethullah Gülen, who leader’s claim is behind last year’s failed coup against Erdogan.
Mr Yildirim said: “We want the USA to extradite to Turkey the person behind the failed coup and the person behind the Gulen movement – these are very important conditions for us to trust the USA and the American administration.
“We are expecting them to take steps in this direction.
“We don’t want them to give us big words and go behind our backs and say other things.
“We believe they are serious about trying to mend relations with Turkey.”
According to Ankara, the current policy on the Middle East from the Trump administration is likely to be changed.
Erdogan and his administration believe the current stance is little more than a hangover from the Obama days.
Mr Yildirim said: “This plan is not the Trump administration’s plan. This plan was already conceived by the previous administration.
“We do not agree on this topic and we told them we do not agree.
“The new administration with Turkey will be a better collaboration.
“The USA considers the PKK a terrorist organisation, exactly as Turkey does.”
The prime minister told reporters in London the groups being supported by the USA are terrorists “in different clothes”.
He said: “With the Raqqa operation in Syria there has been a difference of opinion about the Raqqa operation – but regarding our relationship with Nato, our strategic partnership with the US – it will not be destroyed by this, the mistake will be fixed.
“They are terrorist organisations, just changing clothes.
“They are terrorists who fight for whoever gives them money. The US sees they are very enthusiastic to kill people, so they may use them.
“This is not the way to solve the issue.
“This problem will web fixed. Since great minds think alike.”
President Erdogan will meet President Trump in Washington next week.